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Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis.

Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation By similarity. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression.

EMBO J. Cancer Inst. Genes Dev. Cell Mol. Cancer Res. Brain Res. Alternative name s :. Thyroid transcription factor 1 Short name:. Nucleus nucleoplasm Source: UniProtKB Inferred from direct assay i "The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription.

By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'. Expressed in restricted regions of the developing brain within the diencephalon, in parts of the hypothalamus and neurohypophysis, and in the telencephalon.

P With Exp. The information is filed in different subsections. Length: Mass Da : 38, It is useful for tracking sequence updates. The algorithm is described in the ISO standard.

Full view. These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary citable accession number'.

See complete history. Do not show this banner again. Activator , DNA-binding , Repressor. Biological rhythms , Transcription , Transcription regulation.

Recommended name: Homeobox protein Nkx This is known as the 'taxonomic identifier' or 'taxid'. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.

Rat genome database More RGD i. PaxDb, a database of protein abundance averages across all three domains of life More PaxDb i.

PRIDE i. PhosphoSitePlus i. Protein interaction database and analysis system More IntAct i. Molecular INTeraction database More MINT i.

SMR i. Database of comparative protein structure models More ModBase i. PDBe-KB i. In addition, a band consistent with TIMP-2 occurred in all samples on reverse zymography.

A serine proteinase with a broad band around kDa was found in 2 of the 11 AMD vitreous samples. We use cookies to ensure that we give you the best experience on our website.

If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

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Thyroid transcription factor 1 Short name:. Nucleus nucleoplasm Source: UniProtKB Inferred from direct assay i "The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription.

By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.

Expressed in restricted regions of the developing brain within the diencephalon, in parts of the hypothalamus and neurohypophysis, and in the telencephalon.

P With Exp. The information is filed in different subsections. Length: Mass Da : 38, It is useful for tracking sequence updates. The algorithm is described in the ISO standard.

Full view. These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary citable accession number'.

See complete history. Do not show this banner again. Activator , DNA-binding , Repressor. Biological rhythms , Transcription , Transcription regulation.

Recommended name: Homeobox protein Nkx This is known as the 'taxonomic identifier' or 'taxid'. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.

Rat genome database More RGD i. PaxDb, a database of protein abundance averages across all three domains of life More PaxDb i.

PRIDE i. PhosphoSitePlus i. Protein interaction database and analysis system More IntAct i. Molecular INTeraction database More MINT i.

SMR i. Database of comparative protein structure models More ModBase i. PDBe-KB i. Relative evolutionary importance of amino acids within a protein sequence More EvolutionaryTrace i.

InParanoid i. Database for complete collections of gene phylogenies More PhylomeDB i. Conserved Domains Database More CDD i. Database of protein disorder More DisProt i.

Integrated resource of protein families, domains and functional sites More InterPro i. We use cookies to ensure that we give you the best experience on our website.

If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again.

Click 'Find out more' for information on how to change your cookie settings. Continue Find out more. Publications Matrix metalloproteinases and their inhibitors in human vitreous.

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